Вакансия закрыта работодателем

Опытные биоинформатики: ML, DNA-seq, OMICs

в Сlarivate Analytics
Город Москва, Russian Federation
Опубликовано 25.09.2017
Категория Биоинформатика
Тип вакансии Полная занятость

Обязанности

Your Team

Clarivate Analytics accelerates the pace of innovation by providing trusted insights and analytics to customers around the world, enabling them to discover, protect and commercialize new ideas faster. We own and operate a collection of leading subscription-based services focused on scientific and academic research, patent analytics and regulatory standards, pharmaceutical and biotech intelligence, trademark protection, domain brand protection and intellectual property management. Clarivate Analytics is a company with over 4,000 employees, operating in more than 100 countries and owns well-known brands that include Web of Science, Cortellis, Derwent, CompuMark, MarkMonitor, and Techstreet, among others.

Our Life Sciences Division supplies thousands of customers with cutting-edge technologies and comprehensive manually curated data resources. For more than 10 years, our team has been at the forefront of the systems biology industry, providing advanced bioinformatics and personalized medicine research and products to pharmaceutical companies, clinical centers, and non-profit organizations globally.

We are a multi-disciplinary, diverse group of scientists who enjoy working together and with customers on developing new technologies, algorithms, and solutions. We create and apply state of the art bioinformatics approaches to address real-life challenging problems in pharmaceutical R&D, such as drug target identification, biomarker discovery, disease mechanisms understanding, patient stratification and personalized medicine. Leading technologies and creative environment make our team a key partner for our customers.

Join our Bioinformatics team, bring your experience and knowledge, learn from us and let us learn from you.

Your Role

Your role is very important to our team.

We are always looking for talented scientists to grow and develop our team and currently we are looking for an experienced bioinformatician who will work with our clients, from pharmaceutical companies and clinical centers as well as non-profit organizations, on advanced statistical and functional analysis of OMICs data generating hypotheses on disease mechanisms, drug response biomarkers, and drug targets. One of your key areas of focus will be research and development for our personalized medicine technology and solutions.  In your projects, you will apply state-of-the-art bioinformatics tools as well as our advanced proprietary Systems Biology Platform; you will also develop new approaches and techniques to address complicated and interesting scientific questions, publish results of your research in scientific journals, and participate in the implementation of the approaches in working tools and commercial software. In addition to research activities, you will also participate in business and strategy development by scoping with customers their scientific needs and transforming these needs into solutions.

Требования

Position 1: OMICs

Your Knowledge, Skills, and Abilities

  1. Retrieval, statistical analysis, integration, annotation of OMICs data: microarray data, NGS data, proteomics data, metabolomics data and other types of OMICs data. Broad experience with machine learning is required.
  2. Experience with pathway and network analyses. Experience with Ingenuity Pathways and MetaCore will be an advantage
  3. Proficiency in statistical programming languages (R – required, MatLab – preferred), scripting languages (Perl, Python), database querying languages (SQL)
  4. Knowledge of molecular biology and human genetics is required; knowledge of normal and pathological signaling pathways is preferred
  5. Excellent written and verbal communication skills with the ability to conduct regular presentations and write scientific texts/articles
  6. Self-starter, able to set priorities and work independently

Experience

  • Ph.D. in Bioinformatics, Statistics, Systems Biology or a related field
  • A minimum of two to three years of relevant work experience in bioinformatics or computational biology in a professional setting, preferably in a biotechnology, pharmaceutical, or healthcare setting.

 

Position 2: DNA-seq

Your Knowledge, Skills, and Abilities

  1. Evaluation and design of sequencing-based projects studying the genomic basis of human disease, especially cancer.
  2. Deep knowledge of the development, use, and management of bioinformatics pipelines for genomic data processing, analysis, and mining in the context of human disease, especially cancer.
  3. Interpretation and integration of genetic changes in cancer including mutations, gene expression data, copy number and structural variation.
  4. Demonstrated experience with biostatistics and analysis of datasets from clinical studies.
  5. Proficient in high-performance computing, Unix/Linux shell, R, Python, and version control software
  6. Ability to work independently and within a multidisciplinary team of diverse collaborators including oncologists, computer scientists, biologists, and biostatisticians.
  7. Excellent written and verbal communication and problem-solving skills, with exceptional attention to detail
  8. Self-motivated and disciplined, with advanced time and project management skills

Experience:

Ph.D. in genomics, bioinformatics or computational biology in addition to a working knowledge of current genomic and functional high-throughput assays, and related analysis methods.

 

Position 3: Machine Learning

Your Knowledge, Skills, and Abilities

  1. Deep knowledge of a wide range of machine learning techniques, statistical modeling, classification, and regression. Proven extensive experience in the application of machine learning techniques, statistical modeling, classification and regression to analysis of OMICs data and other types of big biological data.
  2. Understanding of what statistical approaches are likely to be effective across a range of scenarios.
  3. Fluency in R. Fluency in Python is preferable.
  4. Experience with pathway and network analysis is advantageous.
  5. Knowledge of molecular biology and human genetics is an advantage
  6. Excellent written and verbal communication skills with the ability to conduct regular presentations and write scientific texts/articles
  7. Self-starter, able to set priorities and work independently

Experience:

  • Ph.D. in Bioinformatics, Statistics, Computer Science, Systems Biology or a related field
  • A minimum of four years of relevant work experience in bioinformatics or computational biology in a professional setting, preferably in a biotechnology, pharmaceutical, or consulting setting.

Условия

At Clarivate Analytics Bioinformatics team, we believe that our scientists are our most important asset and it is our priority to make it a great place to work.

This position provides unique opportunities for further professional growth:

  • Enhance your vision and improve your network by working in close collaboration with diverse leading organizations, including pharmaceutical companies, clinical centers, and research foundations
  • gain unique expertise with internal access to vast data resources at Clarivate Analytics, the largest provider of molecular and R&D information in the industry
  • extend your technical skills by working in a team of bioinformaticians, biologists, chemists, knowledge management specialists and pharmaceutical industry experts with complementary skill sets to address challenges in biomarker discovery, target identification, drug repositioning, NGS data analysis, network biology and other applications
  • simply enjoy being a part of a global business and a high-performing synergistic team

Другие важные условия:

  • полный рабочий день
  • офис в Москве
  • зарплата хорошая, обсуждается
  • присылайте CV и мотивационное письмо на английском
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