Bioinformatics scientist

в BostonGene (посмотреть профиль)
Город Moscow, Russian Federation
Опубликовано 02.11.2020
Категория Биоинформатика
Тип вакансии Полная занятость
Адрес м. Павелецкая, Шлюзовая набережная, 6/4

Обязанности

  • Participate in the research on oncogenesis and tumor properties integrating WES, WGS, RNAseq, scRNAseq, and Methyl-seq data analysis;
  • Develop algorithms and analyze NGS data (WES, WGS, RNAseq, scRNAseq, Methyl-seq);
  • Study the basics of tumor oncogenesis, participate in projects aimed to discover personalized biomarkers of therapeutic efficacy;
  • Analyze tumor biology;
  • Analyze scientific literature and expand the BostonGene knowledge base on oncogenesis/tumor’s molecular and cellular characteristics;
  • Analyze the [NM5] mechanism of action of drugs at the molecular and cellular level;
  • Participate in the development of a model to describe the molecular and cellular properties of a tumor.

Требования

Experience working with RNAseq data

  • identifying somatic mutations from genomic sequencing data;
  • estimating changes in the copy number of genome elements and their structural rearrangements from sequencing data;
  • knowledge of fundamentals of immunology/cell biology;
  • knowledge of molecular biology and cell signaling;
  • knowledge of the molecular basics of modern targeted and immune antitumor therapies is encouraged;
  • experience with scientific literature and scientific databases;
  • fluency in English sufficient for fluent reading and understanding of scientific articles;
  • background in experimental work in biochemistry /molecular biology is a plus;
  • experience with Python/pandas, R;
  • knowledge in machine learning is a plus.

Условия

  • Full-time position, permanent contract, flexible working hours;
  • Versatile professional environment: bioinformatics, biologists, physicians, and software developers who united to save people’s lives;
  • Office within walking distance from Paveletskaya metro station;
  • Competitive salary and medical insurance.
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