Pavel S.
Senior scientist in sctructural bioinformatics, polymer science, and protein scienceIndustry: Senior scientist or Principal scientist
Academia: Group leader or Assist/Assoc Professor (reseaerch)
EU/UK
Topics/keywords: Computational design of polymer-based delivery systems; structural bioinformatics, computational drug design, protein science, polymer science, protein-protein interactions, intrinsically disordered proteins associated with human diseases (including amyloids), protein-polymers and protein-membrane complexes, molecular chaperones and artificial chaperones, targeted delivery, biotechnology-oriented enzyme applications, etc.
Последнее обновление резюме | 19.09.2023 |
Адрес | Russian Federation |
Электронная почта | Заблокировано |
Опыт
researcher, senior researcher (since 2018), and leading researcher (since 2020)
junior researcher
Образование
Lomonosov Moscow State University
Lomonosov Moscow State University
В чем вы сильны?
I am an expert in protein science, polymer science, and, more important, their combination. I am strong in structural bioinformatics, especially molecular modeling of proteins and protein complexes, intrinsically disordered proteins, and polymers. I also have a strong expirience in wet protein science with a focus on protein stability, enzyme activity, and artificial chaperones.
Hard skills:
Biochemical routines, protein biochemistry, study of protein-polymer colloids;
Physicochemical methods for protein&polymer research, including differential scanning calorimetry, circular dichroism spectroscopy, isothermal titration calorimetry, surface plasmon resonance, dynamic light scattering, analytical ultracentrifugation, etc; some experience with and understanding of NMR, CryoEM, MS, etc.
Structural bioinformatics; protein homology modeling; atomic model building and refinement from CryoEM data; small molecule docking, protein-protein docking;
Molecular dynamics simulations (proteins, polymers, membranes, DNA, IDPs), both atomistic and coarse-grained, REMD; HPC-based computations;
Bioinformatics routines, alignment and phylogeny reconstruction, bioinformatics of biological sequences; programming (Java, Python, bash scripting, etc);
Расскажите о себе что-нибудь еще: публикации, конференции, хобби
Papers: Scopus 36515735000, Google Scholar, or ORCID 0000-0001-7759-6445
Grants attracted as a leader from Russian Foundation for Basic Researches and Russian Science Foundation (~250k € in total);
Supervision of a PhD student (defended in 2022);
Supervision of Master's thesis and Course projects of MSU students (>10);
Management and contacts with clients in the Dept. of Physical methods of measurements, a core facility center in Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University;
Holding practical courses on physicochemical methods for investigation of biomolecules” for a joint DFG-RFBR project;
Non-scientific leadership: Leading groups of 5-13 people in autonomic trekking and mountaineering (Tian Shan, Pamir-Alay, Mongolia).