Professional skills and competencies:

Languages

Russian (mother tongue), English (professional working proficiency), Finnish (limited working proficiency)

Leadership

Supervision of students, project leading (MSc thesis), organization of popular-science events

Computer skills

Microsoft Office tools, GraphPad Prism, Statistica, ImageJ, CellProfiler, CellProfiler-Analyst, LaTex, QuPath,

Technical skills:

Advanced:

–Handling of small laboratory animals (including mice, rats, guinea pigs) and various pharmacological in vivo tests including behavioral tests, analgetic activity; acute and chronic toxicity; necropsy skills and general knowledge of pathological anatomy; 

–Tools for pharmacokinetic characterization of drugs: intravenous, subcutaneous, intraperitoneal, intramuscular, etc. methods of administration; biosampling (retroorbital, intracardial, etc., for histological examination); computational calculations of pharmacokinetic parameters etc.;

– Independent planning and setting up experiments;

– Preparation of analytical reviews of scientific literature, presentation to an audience with different backgrounds;

– Strong ability to work with documentation, drawing up methodologies and SOPs.

Moderate:

–Light and electron microscopy (sample preparation, staining (immunohistochemistry), image analysis using ImageJ, CellProfiler, CellProfiler-Analyst, QuPath);

–Handling of mammalian cells in vitro (regular cell lines and primary cells) and some assays (toxicity, staining);

Beginner:

– Traditional molecular biology techniques (Western blot, transfection of eukaryotic cells, ELISA);

– Programming (Python, R).

• Peer-reviewed scientific articles

Total number of publications in peer-reviewed journals is 23 (not listed, the full list is available here https://scholar.google.com/citations?hl=en&user=9KrCVP4AAAAJ); 5 most important which demonstrate independence and high scientific impact of the applicant’s research:

1. Kotliarova A. et al. A newly identified monoterpenoid-Based Small Molecule Able to Support the Survival of Primary Cultured Dopamine Neurons and Alleviate MPTP-Induced Toxicity In Vivo. Molecules (2022). IF=4.9
2. Kotliarova A and Sidorova YA Glial Cell Line-Derived Neurotrophic Factor Family Ligands, Players at the Interface of Neuroinflammation and Neuroprotection: Focus Onto the Glia. Front. Cell. Neurosci. (2021) IF=3.9
3. Haider, M. S., Mahato, A. K., Kotliarova, A., Forster, S., Böttcher, B., Stahlhut, P., et al. (2021). Biological activity In vitro, absorption, BBB penetration and toxicity of nanoformulation of BT44, a RET agonist with disease-modifying potential for the treatment of neurodegeneration. Biomacromolecules (2022) IF=6.9
4. Álvarez-Suárez, A.S.; Dastager, S.G.; Bogdanchikova, N.; Grande, D.; Pestryakov, A.; García-Ramos, J.C.; Pérez-González, G.L.; Juárez-Moreno, K.; Toledano-Magaña, Y.; Smolentseva, E.; Paz-González, J.A.; Popova, T.; Rachkovskaya, L.; Nimaev, V.; Kotlyarova, A.; Korolev, M.; Letyagin, A.; Villarreal-Gómez, L.J. Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings. Micromachines (2020) IF=2.5
5. Kotlyarova A, Ponomarev K, Morozova E, Korchagina D, Suslov E, Pavlova A, Tolstikova T, Volcho K, Salakhutdinov N. The effect of 3,7-diazabicyclo[3.3.1]nonanes containing monoterpenoid moieties on the physical activity of mice. J.Res.Pharm. (2020) IF=0.87

• Non-refereed scientific articles

Presenting author at international scientific meetings, including 6 poster presentations and 2 oral presentations (see “invited talks”) and a co-author in 14 conference abstracts (not listed, the full list is available here: https://www.elibrary.ru/author_items.asp).

• Сo-author of seven RU patents.
• Research supervision and leadership experience

1. December 2022 - Present time. Two project students Shachaf Kolan and Noga Erez at Ben-Gurion University of the Negev Medical Faculty (Beersheba, Israel).
2. August 2021 – October 2021. Lab placement supervision for Stadin ammattikoulu students Muhammad Al-Khiat and Hadeel Bayati (2 students), University of Helsinki (Finland).
3. September 2015 - May 2016. Olga Oleinik, MSc student (Pharmacy), NSMU (Novosibirsk, Russia) (principal supervisor)

• Teaching merits

1. September 2017 – December 2017. Advanced pedagogical training “Pedagogy and psychology, information technology” for teachers, NSMU (Novosibirsk, Russia)
2. September 2015 - July 2019. Responsible teacher “Basic course of Pharmacology”. Preparing lectures, course materials, tests. NSMU (Novosibirsk, Russia)

• Scientific and societal impact

2018 – 2020. Co-organizer of yearly Day of Russian Science outreach events for popularizing scientific knowledge (Novosibirsk, Russia)

• Invited presentation and talks:

1. Three Minute Thesis (3MT), Early Careers Researchers Online Programme with the University of York, 2021.
2. UK - Russia Workshop: Biomaterials for Drug and Cell Delivery, Manchester, UK, 2019.
3. International Multi-Conference on Engineering, Computer and Information Sciences (SIBIRCON), Novosibirsk, Russia, 2019 https://youtu.be/e8tmMMPmkoE (RUS)
4. International Multi-Conference on Engineering, Computer and Information Sciences (SIBIRCON), Novosibirsk, Russia, 2017 https://youtu.be/2gke91P3qBs (RUS)

• Research communication and dissemination activities:

1. 25.05.2022 Popular science lecture focused on lay public including school children https://youtu.be/Cgol0Sm1wr8
2. 4.06.2020 Video interviews for TV “Novosibirsk News” and for State TV and Radio Company "Novosibirsk" about our recent research results with new interferon-lambda formulation and it’s antiviral properties in vivo, https://youtu.be/7ix6IbAKzpQ (from 1:39, RUS), https://youtu.be/QNri9v_0-1U (from 1:25, RUS)
3. 26.05.2020 Popular article describing the use of recently RICEL’s developed pegylated interferon-lambda formulation against Sars-Cov-2, https://news.ru/health/korognavirus-lekarstvo-lechenie/ (RUS)
4. 11.05.2018 Video interview for State TV and Radio Company "Novosibirsk" to describe results of my PhD project about new pharmaceutical formulation of lithium and its neuroprotective effect https://youtu.be/djT_d8hhBsI (from 1:01, RUS)